Center for Nanotechnologies (CNT)
under the aegis of Romanian Academy

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L1: Laboratory of Nanotechnology
Affiliated to the Romanian Academy (of Sciences)

Laboratory Head Dr. Irina Kleps (irina.kleps@imt.ro)

Mission: Nanomaterials and nanostructures: design, modelling/ simulation and technological experiments.

Main areas of expertise: The research activities carried on in Laboratory of Nanotechnology can be divided into four areas which are: Functional nanomaterials, Nanobiosystems, Nanophotonics and Microelectromechanical Systems. The main research direction in Functional nanomaterials area is study of nanostructured silicon based or composite materials, from preparation to surface functionalisation and integration in complex systems. The Nanobiosystems area focuses on utilizing the various technologies developed in nanofabrication and MEMS to study and solve biological issues. Biomolecular patterns in microarrays, integration of sensing elements onto biochips for study of bioreactions, and implantation of active device elements in cells to study cellular biochemistry are examples of research activities being carried out. The Nanophotonics area is represented by two directions, porous silicon with emission in the visible spectrum for microparticles visualisation in vitro and for optical biosensors and metallic nanoparticles (Au, Ag) on silicon substrates for SERS/ SEIRS applications.The Bio-Micro- Electromechanical Systems (Bio-MEMS) area focuses on the design, modelling/simulation and fabrication of new complex devices on silicon for applications in many interdisciplinary areas; recently new results in biochips, or microfluidicsystems as laboratory-on-a-chip with applications in biomedicine and environmental monitoring as well as in the development of new fuel cell devices as clean energy sources were obtained.

International participation

• “Drug delivery system based on microreservoirs array with porous silicon resorbable membrane caps”, Romanian-Greece International Cooperation, Decembrie 2005-2008;
• “Nanostructured silicon for optical biosensors”, Romanian-Italian International Cooperation, 2006-2008;
• “Suface engineering techniques to investigate inorganic-biomolecular interfaces”, research project in the frame of NoE-NANOFUN-POLY; “European FP6 Network: Nanostructured and Functional Polymer-Based Materials and Nano-composites;
• A “system-in-a-microfluidic package” approach for focused diagnostic DNA microchips-DNASIP, MNT-ERA, 2008-2010.

Research team has multidisciplinary expertise and is composed by 4 senior researchers (with background in physics, chemistry), 5 PhD students (with background in physics, chemistry, computers and specializations in pharmacy and bio-chemistry).

Award: Marioara Avram, Irina Kleps si Anca Angelescu,Gold medail to the EUREKA 2008- The Belgian and International Trade Fair for Technological Innovation, Brussels, Procedure of realization a spin valve magnetotransistor.

EXPERIMENTAL LABORATORIES

  • Centre of Nanotechnologies an interdisciplinary group, involving a few RTD laboratories, was developed as follows: Laboratory of nanotechnology (L1) created the following experimental laboratories;
  • Experimental laboratory for “Microarrays”, or NanoBioLab, with the following main equipments: - Microarray Scanner - GeneTAC UC4 (Genomic Solutions Ltd., UK) - Micro Plotter - Omni Grid ( Genomic Solutions Ltd., United Kingdom); Project: Integrated Research Network Devoted to Nanobiotechnology for Health (Romanian Nanomedicine Network) RO-NANOMED (2005-2008).
  • Experimental laboratory for surface spectroscopy, with: - Electrochemical Impedance Spectrometer PARSTAT 2273 (Princeton Applied Research); - Scanning electrochemical microscope (SECM);
  • Experimental laboratory for X-Rays diffraction, with: - X-ray Thin film Diffraction System (triple axis rotating anode) - SmartLab - 9kW rotating anode, in-plane arm (Rigaku Corporation Japan);
  • Experimental laboratory for nanoparticles, with: - DelsaNano Zeta Potential and Submicron Particle Size Analyzer - Allegra X-22 (The Beckman Coulter); - Fluorescence spectrometer; - Centrifuge - Allegra X-22 (Beckman Coulter);
Monica Simion (monica.simion@imt.ro) working on the Micro Plotter to prepare a protein C reactive microarray slide
Mihaela Miu (mihaela.miu@imt.ro) investigating the electrocalalytic activity of the gold nanoparticle electrode array with SECM
Teodora Ignat (teodora.ignat@imt.ro) is working for gold electrode cleaning by cyclic voltammetry
Adina Bragaru (adina.bragaru@imt.ro) working for nanoparticle centrifugation and characterization
Mihai Danila (mihai.danila@imt.ro) introducing in the sample in the XRD for investigation the Pt nanocystallite orientation and size

 

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Last update: December, 2009