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About
During this project we are investigating, using multidisciplinary
fundamental research activities, the most advanced innovative aspects
of: (1) interactions within supra-molecular biological systems; (2)
observation of new interactions; (3) solving the mechanisms which
trigger the behavior of biophysical systems; (4) thorough
investigation of the hemodynamic structures and processes at the
molecular and cellular level; (5) development of new concepts
regarding the electrophoresis, dielectrophoresis and magnetophoresis
phenomena; (6) applications of these phenomena for theoretical
formulation and development of a lab-on-a-chip. For sorting,
manipulating and counting biocells. The need to approach such a
thematic is justified by the benefits of developing such a
microfluidic device: reduced size, ability to separate biological
cells according to size and properties, ability to perform preliminary
analysis, all this making it priceless for blood analysis laboratories
for sorting, manipulating and analyzing the bioparticles.
Main objectives:
(1) molecular
dynamic studies of the electrophoretic, dielectrophoretic and
magnetophoretic regimes of biomolecules.
(2)
thermo-electro-magnetic modeling and complex structural analysis
studies.
(3) formulation of
self-consistent theories for describing the interaction of
nano-biosystems with the electromagnetic field.
(4) numerical
simulations with specialized software adapted for the optimisation of
the results.
(5) development of
an advanced lab-on-a-chip concept for dielectrophoretic and
magnetophoretic separation of biocells.
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